Antimicrobial peptides play an important role in innate immunity, and are produced in the blood, saliva and hemolymphs of numerous species where they are involved in the fight against bacterial infection. Their actions are mostly lytic, with some peptides showing clear selectivity for Gram-positive and/or negative organisms over mammalian cells. Interestingly, lytic peptides are also present in spider venoms, where they are used both to propagate the actions of other toxins and to digest prey.
Accordingly, the Toxinomics Foundation has an ongoing program focusing on the identification and development of novel antimicrobial peptides derived from the blood, saliva, lymphs and venoms of numerous species ranging from arthropods to man. A first set of 64 novel antimicrobial peptides has been identified to date, with others being available in 2012. Please visit our products page for further details.